Strict glycaemic control could prevent such complications in chronic diabetes. This study was conducted for 4 months i.e., May - Aug 2015 (4 Months) and was undertaken in two phases i.e.,: 1) Baseline and 2) 6 weeks supplementation.īefore the commencement of the study, all 45 participants were gathered together to inform the Aim & objective of the study, detailed study methodology, benefits expected and risks associated with the study as well as the freedom of individual to participate or withdraw from research at any point of time.ĭiabetes mellitus can cause a wide range of complications affecting almost any system of the body. This was a pre and post supplementation comparative study. statins, hormone replacements, antihypertensive drugs interfering with lipid profile or blood sugar were not included in this study. Subjects under medications like oral hypoglycaemic, hypolipidemic drugs i.e. Subjects suffering from any known chronic disorders, known diabetics, hypertensive with dyslipidaemia, addiction to alcoholism or tobacco smoking were excluded from the study.
They were randomly enrolled into Group A, Group B and Group C. Forty five healthy MBBS students i.e., 31 male and 14 female MBBS students having routine diet of hostel canteen within the age group of 18 to 25 years were included in the study. This Randomized Controlled study was conducted in the Department of Biochemistry, All India Institute of Medical Sciences, Bhubaneswar. An attempt was also made to find the role of Guava fruit supplementation on Body Mass Index (BMI) and Blood Pressure (BP). So, this study was conducted with an objective to evaluate the effect of ripe guava (with peel and without peel) fruit supplementation on blood glucose and lipid profile in healthy human subjects. Till now no human study has been conducted revealing the role of ripe guava fruit with peel and without peel on blood sugar and lipid profile.Īs diabetes mellitus has emerged as a major urban health problem in India, observing the potential of natural products especially by supplementing fruits in regular diet and studying their effect in preventing diabetic complications has become important research avenue. guajava had shown hypoglycaemic as well as hypolipidemic and hepatoprotective effect but the ripe fruit peel has been found to have hyperglycaemic activity in diabetic rats.
#Guava nectar juice free#
Although the fruit of P.guajava is known to contain free sugar, yet the fruit juice showed hypoglycaemic effect in Streptozotocin (STZ) induced diabetic rats. Recently guava fruit water extract showed impressive efficacy in improving dyslipidaemia in animal models. Though the hypoglycaemic activity of guava leaves is well documented and guava leaf extract tea is available in market, the role of guava fruit in regulating blood sugar and lipid profile in human is still not clear.
The administration of ethanolic extract of P.guajava leaf showed hypolipidaemic and hypoglycaemic effect in Alloxan induced diabetic rats.
Psidium guajava (P.guajava) leaves have been reported to have hypoglycaemic effect on blood glucose level of normal rats as well as Streptozotocin (STZ) induced diabetic rats. Since long time, different parts of Guava tree have been extensively studied for its medicinal role. So, it is considered as poor man’s apple of tropical and sub-tropical countries. Guava fruit is included among the super-fruits with low calorie profile with high dietary fibre, rich in antioxidant vitamins i.e., Vitamin C, Lutein, Beta carotene as well as minerals. Guava ( Psidium guajava Linn.) is a small tropical tree that is widely grown for its fruit that is commonly known for its nutritional, medicinal and pharmacological values.
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